Skip to main content
Fig. 4 | Chemistry Central Journal

Fig. 4

From: Structural optimization and evaluation of novel 2-pyrrolidone-fused (2-oxoindolin-3-ylidene)methylpyrrole derivatives as potential VEGFR-2/PDGFRβ inhibitors

Fig. 4

Compounds 7, 1315, and sunitinib inhibited tube formation induced by VEGF. a Solvent control; b VEGF (10 ng/ml) and 0.1 μM sunitinib; c VEGF (10 ng/ml) and 0.10 μM 7; d VEGF (10 ng/ml) and 0.10 μM 13; e VEGF (10 ng/ml) and 0.10 μM 14; f VEGF (10 ng/ml) and 0.10 μM 15; g VEGF (10 ng/ml) and 0.50 μM sunitinib; h VEGF (10 ng/ml) and 0.50 μM 7; i VEGF (10 ng/ml) and 0.50 μM 13; j VEGF (10 ng/ml) and 0.50 μM 14; k VEGF (10 ng/ml) and 0.50 μM 15; l VEGF (10 ng/ml) and 1.0 μM sunitinib; m VEGF (10 ng/ml) and 1.0 μM 7; n VEGF (10 ng/ml) and 1.0 μM 13; o VEGF (10 ng/ml) and 1.0 μM 14

Back to article page
\