Entry | Target compounds | Method-1 (diamine + cinnamic acid) | Method-2 (2-MeBz + aldehydes) | m.p (°C) | ||||
---|---|---|---|---|---|---|---|---|
Time (h) | Temp (°C) | Yield (%) | Time (h) | Temp (°C) | Yield (%) | |||
5a |
| 5 | 160 | 74 | 6 | 160 | 75 | 202–204 |
5b |
| 5 | 160 | 68 | 6 | 160 | 70 | 178–180 |
5c |
| 5 | 160 | 80 | 6 | 160 | 76 | 130–132 |
5d |
| 5 | 150 | 73 | 6 | 160 | 76 | 210–212 |
5e |
| 5 | 150 | 78 | 6 | 160 | 76 | 198–200 |
5f |
| 5 | 160 | 74 | 5 | 160 | 76 | >240 |
5g |
| 5 | 160 | 68 | 5 | 150 | 66 | 100–102 |
5h |
| 5 | 150 | 78 | 5 | 150 | 74 | 108–110 |
5i |
| 5 | 160 | 75 | 5 | 150 | 75 | >220 |
5j |
| 5 | 150 | 76 | 6 | 160 | 74 | 200–220 |
5k |
| 6 | 160 | 75 | 5 | 150 | 75 | 190–210 |
5l |
| 5 | 150 | 75 | 6 | 160 | 74 | 202–204 |
5m |
| 5 | 160 | 74 | 5 | 150 | 75 | 205–210 |
5n |
| 6 | 150 | 75 | 6 | 160 | 75 | 210–220 |