From: Optimization of enzymatic esterification of dihydrocaffeic acid with hexanol in ionic liquid using response surface methodology
Independent variable
Independent variable level
Low (−1)
Medium (0)
High (+1)
Axial (−1.66)
Axial (+1.66)
Reaction timea
24
48
72
8.0
88.0
Reaction Tempb
40
50
60
33.3
66.7
Conc. of hexanolc
2.2
5.5
8.8
0.0
11.0
Enzyme amountd
15
25
35
8.3
41.6