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Table 3 Gadolinium based nanocomposites for simultaneous delivery of drug and contrast agents

From: Gadolinium-based layered double hydroxide and graphene oxide nano-carriers for magnetic resonance imaging and drug delivery

Carrier

Contrast agent

Active agent

Cell type

Remark

Ref

Year

Mg–Al-LDH

Gd/Au

DOX

Cervical cell (Hela)

Low cytotoxicity in vitro and good CT and T1-weighted MR imaging capabilities

[43]

2013

GO-PEG

Gd

DOX

Human liver cell (HepG2)

Shows greater tumor targeting imaging efficiency

[70]

2012

NGO-PAMAM

Gd

EPI

Glioblastoma (U87)

Inhibit cancer cells growth and good MRI contrast for tumor identification

[56]

2014

GO-DTPA

Gd

DOX

Human liver cell (HepG2)

Improved MRI T1 relaxivity with better cellular MRI contrast and with a substantial cytotoxicity against cancer cells

[55]

2013

Gd(OH)3:Mn

Gd

DOX

Breast cancer cell (MDA-MB-231)

High cytotoxicity towards the cancer cells as well promising paramagnetic activity and radiation treatment for cancer

[59]

2016

Fibre

Gd DTPA

Indomethacin

Potential theranostic agents

[58]

2016