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Table 3 Recovery of quality control samples for determining the concentration of VNT in human plasma and RLMs matrices

From: Liquid chromatography tandem mass spectrometry method for the quantification of vandetanib in human plasma and rat liver microsomes matrices: metabolic stability investigation

Nominal concentration (ng/mL)

Human plasma

RLMs

20 ng/mL

150 ng/mL

400 ng/mL

20 ng/mL

150 ng/mL

400 ng/mL

Meana

19.36

150.78

400.38

19.47

151.59

402.51

Recovery (%)

96.80

100.52

100.10

97.35

101.06

100.63

Standard deviation (SD)

0.43

1.29

6.4

0.31

0.5

3.47

Precision (% RSD)

2.22

0.86

1.6

1.61

0.33

0.86

  1. aAverage of six determinations
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BMC Chemistry

ISSN: 2661-801X

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