Table 4 Drug-like properties of the quinazolines 1–3
Sample number | Molecular weight (g/mol) | TPSA | LogS | LogP | HBA | HBD |
|---|---|---|---|---|---|---|
1 | 570.49 | 127.15 | −9.26 | 4.86 | 5 | 3 |
2 | 475.39 | 118.41 | −8.31 | 3.52 | 5 | 2 |
3 | 552.48 | 101.62 | −9.63 | 5.55 | 5 | 1 |
Sample number | Molecular weight (g/mol) | TPSA | LogS | LogP | HBA | HBD |
|---|---|---|---|---|---|---|
1 | 570.49 | 127.15 | −9.26 | 4.86 | 5 | 3 |
2 | 475.39 | 118.41 | −8.31 | 3.52 | 5 | 2 |
3 | 552.48 | 101.62 | −9.63 | 5.55 | 5 | 1 |