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Table 1 The inhibitory activities of the tested compounds against three tumor cell lines compared with reference standards

From: Molecular docking and biological evaluation of some thioxoquinazolin-4(3H)-one derivatives as anticancer, antioxidant and anticonvulsant agents

Sample number

IC50 (µg/ml)

HepG2

MCF-7

HCT-116

1

3.0 ± 0.4

3.1 ± 0.6

4.4 ± 0.9

2

9.5 ± 1.2

9.7 ± 1.8

10.6 ± 2.1

3

3.9 ± 0.6

3.3 ± 0.6

5.7 ± 0.5

Vinblastine sulfate

4.3 ± 0.7

4.6 ± 0.8

2.4 ± 0.3

Doxorubicin

0.5 ± 0.1

0.4 ± 0.1

0.4 ± 0.1

  1. The data are expressed as IC50 value ± standard error
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BMC Chemistry

ISSN: 2661-801X

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