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Table 1 The inhibitory activities of the tested compounds against three tumor cell lines compared with reference standards

From: Molecular docking and biological evaluation of some thioxoquinazolin-4(3H)-one derivatives as anticancer, antioxidant and anticonvulsant agents

Sample number IC50 (µg/ml)
HepG2 MCF-7 HCT-116
1 3.0 ± 0.4 3.1 ± 0.6 4.4 ± 0.9
2 9.5 ± 1.2 9.7 ± 1.8 10.6 ± 2.1
3 3.9 ± 0.6 3.3 ± 0.6 5.7 ± 0.5
Vinblastine sulfate 4.3 ± 0.7 4.6 ± 0.8 2.4 ± 0.3
Doxorubicin 0.5 ± 0.1 0.4 ± 0.1 0.4 ± 0.1
  1. The data are expressed as IC50 value ± standard error