Skip to main content

Table 5 Comparison of anti-bacterial activity of complex 4 with 2,9-dimephen

From: Synthesis, crystallographic, spectroscopic studies and biological activity of new cobalt(II) complexes with bioactive mixed sulindac and nitrogen-donor ligands

Concentration (mg/ml)

Bordetella

E. coli

S. epidermidis

S. aureus

Saccharomyces

G−

G−

G+

G+

Yeast

IZD of 4 (mm)

 

 8

16.2 ± 1.9

12.0 ± 2.0

39 ± 1

25.0 ± 1.5

41.12 ± 0.5

 4

13.7 ± 0.5

–

34.6 ± 0.7

24.3 ± 0.5

41 ± 1

 2

11.4 ± 1.2

–

30.4 ± 1.6

21.9 ± 0.7

35.9 ± 0.5

IZD of 2, 9-dimephen

 

 8

14.6 ± 0.9

–

36.9 ± 1.5

39 ± 1

44 ± 2

 4

9.2 ± 0.5

–

35.5 ± 0.7

35.4 ± 0.5

42 ± 1

 2

8.3 ± 1.2

–

33.0 ± 1.6

31.3 ± 0.7

38.4 ± 0.5