Skip to main content

Table 2 Robustness data for the proposed method

From: Rapid simultaneous determination of indacaterol maleate and glycopyrronium bromide in inhaler capsules using a validated stability-indicating monolithic LC method

Variation Resolution Theoretical plates Assay (%)
IND GLY IND GLY
28% ACN 4.81 4785 4658 99.86 100.23
32% ACN 3.57 4924 4826 100.71 100.96
pH 3.3 4.13 4875 4732 100.49 100.91
pH 3.7 4.32 4817 4715 100.37 100.35
Flow (1.9 mL) 4.42 4858 4715 100.35 100.34
Flow (2.1 mL) 3.91 4894 4737 100.52 100.87
Wavelength 208 (nm) 4889 4734 100.73 101.14
Wavelength 212 (nm) 4862 4719 100.29 100.12
Temperature 33 °C 4.33 4861 4712 100.3 100.24
Temperature 37 °C 4.14 4884 4741 100.61 100.81
Without variation 4.25 4870 4725 100.43 100.62