Table 1 In vitro antimicrobial activities of the synthesized fluorinated compounds tested at 1 mg/mL by well diffusion agar assay and expressed as inhibition zone diameter (mm) in the form of mean ± SD
Tested microorganisms compound code | Fungi | Gram positive bacteria | Gram negative bacteria | |||
|---|---|---|---|---|---|---|
A. fumigatus RCMB 002568 | C. albicans RCMB 005036 | S. pneumoniae RCMB 010010 | B. subtilis RCMB 010067 | P. aeruginosa RCMB 010043 | E. coli RCMB 010052 | |
3a | 0 | 0 | 0 | 0 | 0 | 0 |
3b | 0 | 0 | 0 | 0 | 0 | 0 |
3c | 0 | 0 | 0 | 0 | 0 | 0 |
3d | 16.9 ± 1.2 | 0 | 15.4 ± 0.8 | 18.2 ± 0.6 | 12.4 ± 0.8 | 15.1 ± 1.2 |
3e | 0 | 0 | 0 | 0 | 0 | 0 |
4a | 20.1 ± 1.3 | 0 | 20.6 ± 1.5 | 22.1 ± 1.2 | 17.2 ± 1.5 | 21.3 ± 0.8 |
4b | 16.3 ± 0.5 | 0 | 14.2 ± 0.4 | 17.1 ± 0.6 | 11.2 ± 0.7 | 13.4 ± 0.7 |
4c | 0 | 0 | 15.1 ± 0.7 | 19.8 ± 1.1 | 0 | 0 |
4d | 0 | 0 | 16.3 ± 1.2 | 18.3 ± 0. 8 | 0 | 0 |
Amphotricin B | 23.7 ± 1.2 | 25.4 ± 1.1 | ||||
Ampicillin | 23.8 ± 0.6 | 26.4 ± 0.7 | ||||
Gentamycin | 19.7 ± 0.6 | 24.9 ± 1.5 | ||||