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Table 1 Synthesis of compounds 5 and 6

From: Synthesis and biological evaluation of the new 1,3-dimethylxanthine derivatives with thiazolidine-4-one scaffold

Entry

No

Compound 5

Yield (%)

Entry

No

Compound 6

Yield (%)

1

5a

74

12

6a

50

2

5b

95

13

6b

30

3

5c

95

14

6c

29

4

5d

90

15

6d

28

5

5e

87

16

6e

33

6

5f

91

17

6f

37

7

5g

94

18

6g

50

8

5h

93

19

6h

50

9

5i

93

20

6i

6

10

5j

79

21

6j

54

11

5k

89

22

6k

52