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Table 1 Synthesis of compounds 5 and 6

From: Synthesis and biological evaluation of the new 1,3-dimethylxanthine derivatives with thiazolidine-4-one scaffold

Entry No Compound 5 Yield (%) Entry No Compound 6 Yield (%)
1 5a 74 12 6a 50
2 5b 95 13 6b 30
3 5c 95 14 6c 29
4 5d 90 15 6d 28
5 5e 87 16 6e 33
6 5f 91 17 6f 37
7 5g 94 18 6g 50
8 5h 93 19 6h 50
9 5i 93 20 6i 6
10 5j 79 21 6j 54
11 5k 89 22 6k 52