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Table 7 Predicted mean LogGI50 of Rhazya stricta compounds whose values lower than −6.0 are highlighted in italics may exhibit anti-cancer activity

From: Cheminformatics studies to analyze the therapeutic potential of phytochemicals from Rhazya stricta

MOL ID Name Mean LogGI50 CDRUG
M1 Akummidine −5.408
M2 Antirhine −5.408
M3 3-Epi-antirhine −5.408
M4 Aspidosespermidine −5.726
M5 Condylocarpine −5.726
M6 Dihydrocorynantheol −5.408
M7 Eburnamenine −5.096
M8 Eburnamine −5.096
M9 Eburnamonine −5.096
M10 Geissoschizine −5.048
M11 Isositsirikine −5.408
M12 16-Epi-Z-isositsirikine −5.408
M13 Leuconalm −5.154
M14 Rhazinliam −5.096
M15 Tetrahydrosecamine −4.975
M16 Presecamine −5.726
M17 Sewarine −5.726
M18 Stemmadenine −5.408
M19 Strictamine −5.726
M20 Strictosamide −5.256
M21 Strictosidine −5.937
M22 Taberonine −5.726
M23 Tetrahydrlstonine −5.408
M24 Vallesiachotamine −5.408
M25 Aspidospermoise −5.726
M26 Bhimbrine −5.408
M27 Bhimbrine N-oxide −5.408
M28 Rhazimine −5.726
M29 Rhazimanine −5.408
M30 Rhazicine −5.726
M31 Leepacine −5.726
M32 2-Methoxy 1-2,dihydrorhazamine −5.726
M33 HR-1 −5.096
M34 Vincanicine −5.726
M35 Rhazinaline −5.726
M36 Beta-sitosterol −5.918
M37 Ursolic acid −5.124
M38 Stigmasterol −5.918
M39 Olenaolic acid −5.124
M40 Rhazidigenine (rhazidine) 6.327
M41 N-methylleuconolam −5.154
M42 (+)-Quebranchamine −5.861
M43 Polyneuridine −5.408
M44 (+)-Vincadiformine −5.726
M45 (−)-Vincadiformine −5.726
M46 Secamine 6.298
M47 Vincadine −5.486
M48 Bis-strictidine −5.409
M49 3,14-Dehydrorhazigine −5.726
M50 16-Hydrorhazisidine 6.298
M51 Rhazisidine −5.406
M52 Isorhazicine −5.726
M53 Rhazigine −5.726
M54 Strictisidine −5.726
M55 Strictamine-N-oxide −5.726
M56 Strictigine −5.726
M57 Strictine −5.096
M58 Stricticine −5.726
M59 Strictalamine 6.327
M60 1,2-Dehydroaspidospermine 6.327
M61 Tetrahydrosecodine −5.783
M62 Dihydrosecodine −5.408
M63 Dihydrosecamine 6.298
M64 Dihydropresecamine −5.726
M65 Tetrahydropresecamine −5.726
M66 Rhazinol −5.726
M67 Rhazimol −5.726
M68 Rhazidigenine-N-oxide 6.327
M69 (−)-16R,21R-Omethyleburmanine −5.096
M70 Decarbomethoxy-15,20,16,17-tetrahydrosecodine 6.471
M71 1,2-Dehydroaspidospermidine-N-oxide 6.327
M72 Rhazizine −4.878
M73 15-Hydroxyvincadifformine −5.726
M74 Dihydroburnamenine −5.096
M75 16s,16′-Decarboxytetrahydrosecamine −4.975
M76 Nor-C-fluorocuraine −5.726
M77 Strictibine −5.785