Table 2 Technical specifications and comparison between the two in vitro exposure chambers used in this study: BAT’s exposure chamber and Vitrocell’s mammalian exposure module [40]
BAT exposure chamber | Vitrocell 6/4 CF Stainless mammalian exposure module | |
|---|---|---|
Approximate dimensions | 12 cm Ø × 9 cm H | 10 cm × 16 cm × 13 cm (D × W × H) |
Approximate weight | 0.65 kg | 4.5 kg |
Material | Transparent Perspex® | Polished stainless steel, glass and aluminium |
Capacity | 3 × 24 mm ø culture inserts 6 × 12 mm ø culture inserts 8 × 6.5 mm ø culture inserts 3 × 30 mm ø Petri dishes 1 × 85 mm ø Petri dish | 3 or 4 × 24 mm ø culture inserts 3 or 4 × 12 mm ø culture inserts 3 × 35 mm ø Petri dishes |
Integrated dose tool | 1–3 QCMs | 1–4 QCMs |
Aerosol delivery to ALI | Sedimentation, Brownian motion | Sedimentation, Brownian motion |
Effective residence time | 52 s | 79 s |