Skip to main content

Table 4 Pharmacokinetic parameters of bergapten after intravenous administration of 5 mg kg−1 (n = 8, mean ± SD)

From: The pharmacokinetics, bioavailability and excretion of bergapten after oral and intravenous administration in rats using high performance liquid chromatography with fluorescence detection

Parameters Low (5 mg kg−1)
Tmax (h) 0.0333
Cmax (ng mL−1) 2080 ± 484
AUC(0–tn) (ng mL−1 h−1) 4391 ± 1363
AUC(0–∞) (ng mL−1 h−1) 4474 ± 1323
V/F (L) 0.0027 ± 0.0006
T1/2α (h) 1.74 ± 0.21
MRT(0–tn) (h) 1.80 ± 0.10
MRT(0–∞) (h) 4.05 ± 3.81