Determination of adapalene in gel formulation by conventional and derivative synchronous fluorimetric approaches. Application to stability studies and in vitro diffusion test

Table 4 Precision data for the determination of adapalene applying the proposed approaches

Amount taken (ng/mL)	% found	% RSD	% error
The first approach at 389 nm
Intraday
6.0	100.11 ± 0.85	0.85	0.49
8.0	100.55 ± 0.37	0.37	0.21
10.0	99.88 ± 0.17	0.17	0.10
Interday
6.0	101.05 ± 1.15	1.14	0.66
8.0	99.93 ± 1.22	1.22	0.70
10.0	99.85 ± 0.55	0.55	0.32
The second approach
SDSF at 346 nm
Intraday
6.0	99.67 ± 0.77	0.77	0.44
8.0	99.50 ± 0.25	0.25	0.14
10.0	100.02 ± 0.31	0.31	0.18
Interday
6.0	100.04 ± 0.81	0.81	0.47
8.0	99.02 ± 0.97	0.98	0.57
10.0	98.28 ± 1.13	1.15	0.66
FDSF at 312.45 nm
Intraday
6.0	99.20 ± 0.91	0.92	0.53
8.0	100.08 ± 0.77	0.77	0.44
10.0	99.31 ± 0.42	0.42	0.24
Interday
6.0	101.19 ± 1.37	1.35	0.78
8.0	99.74 ± 0.90	0.90	0.52
10.0	98.11 ± 1.09	1.11	0.65

ISSN: 2661-801X