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Table 3 Application of the proposed approaches for the determination of adapalene in pure form

From: Determination of adapalene in gel formulation by conventional and derivative synchronous fluorimetric approaches. Application to stability studies and in vitro diffusion test

Parameter Amount taken (ng/mL) First approach at 389 nm Second approach Comparison method [3]
Amount found (ng/mL) % found Amount found (ng/mL) % found Amount found (µg/mL) % found
SDSF at 346 nm FDSF at 312.45 nm SDSF at 346 nm FDSF at 312.45 nm
ADP 2.0 2.00 100.00 1.991 1.992 99.54 99.62 20.0 99.22
4.0 4.008 100.20 4.001 3.977 100.02 99.43 30.0 99.88
6.0 5.988 99.80 5.976 5.962 99.59 99.36 40.0 101.15
8.0 8.053 100.66 8.134 8.000 101.68 100.00   
10.0 9.948 99.48 9.915 10.146 99.15 101.46   
12.0 11.956 99.63 11.918 12.023 99.31 100.19   
14.0 14.049 100.35 14.066 13.900 100.47 99.29   
Mean    100.02    99.97 99.91   100.08
SD    0.42    0.88 0.76   0.98
t    1.06 (2.31)*    0.73 (2.31) 0.93 (2.31)   
F    2.88 (5.14)*    1.53 (19.33) 1.16 (19.33)   
  1. N.B. Each result is the average of three separate determinations
  2. * The values between parentheses are the tabulated t and F values at P = 0.05 [15]