TY - JOUR AU - Tolba, M. M. AU - El-Gamal, R. M. PY - 2016 DA - 2016/05/28 TI - Determination of adapalene in gel formulation by conventional and derivative synchronous fluorimetric approaches. Application to stability studies and in vitro diffusion test JO - Chemistry Central Journal SP - 33 VL - 10 IS - 1 AB - Adapalene is a retinoid analogue with actions similar to those of tretinoin. It is used in topical treatment of mild to moderate acne. A survey of the literature reveals that no spectrofluorimetric method has been reported yet for determination of ADP, so it was thought necessary to develop a highly sensitive stability indicating spectrofluorimetric method. SN - 1752-153X UR - https://doi.org/10.1186/s13065-016-0181-0 DO - 10.1186/s13065-016-0181-0 ID - Tolba2016 ER -