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Table 1 Surface tension at the surface-to-air interface for oral OTC formulations

From: Surface tension examination of various liquid oral, nasal, and ophthalmic dosage forms

Solution

Indication

Surface tension (dynes/cm)

Kaopectate® Max

Anti-diarrheal, relives nausea and upset stomach associated with diarrhea

64.7 ± 0.1

CareOne™ Regular Strength Stomach Relief

Antihistamine for allergic reactions, motion sickness, cold, itching, nausea/vomiting, sleep aid

59.6 ± 0.6

CareOne™ Loperamide HCl Oral Suspension

Anti-diarrheal, traveler’s diarrhea

57.8 ± 0.7

Children’s Delsym® Cough + Cold Nitetime

Cough, nasal congestion, symptoms of hay fever (sneezing, runny nose and itchy watery eyes)

49.0 ± 0.6

Chloraseptic® Sore Throat (Phenol/Oral Anesthetic)

Upset stomach (indigestion/heartburn), anti-diarrhea, nausea, belching

44.6 ± 0.2

CareOne™ Multi-Symptom Nitetime Cold/Flu Relief

Pain/fever reducer, cough suppressant, antihistamine

41.5 ± 0.1

CareOne™ Non-Drowsy Daytime Cold/Flu Relief

Pain/fever reducer, cough suppressant, antihistamine

41.3 ± 0.2

CareOne™ Infants’ Ibuprofen Oral Suspension

Pain and fever reducer

39.0 ± 0.7

Halo™ Oral Antiseptic

Oral antiseptic

37.6 ± 0.4

Concentrated Motrin®’s Infants' Drops

Relieves fever and minor aches/pain due to common cold

36.6 ± 0.6

Gastric fluid

 

~36.8 fasting ~30.5 fed

Duodenum fluid

 

~37 fasting ~31.3 fed

Jejunum fluid

 

~30.5 fasting ~30.0 fed