TY - JOUR AU - Naldi, A. C. AU - Fayad, P. B. AU - Prévost, M. AU - Sauvé, S. PY - 2016 DA - 2016/05/06 TI - Analysis of steroid hormones and their conjugated forms in water and urine by on-line solid-phase extraction coupled to liquid chromatography tandem mass spectrometry JO - Chemistry Central Journal SP - 30 VL - 10 IS - 1 AB - In recent years, endocrine disrupting compounds (EDCs) have been found in rivers that receive significant inputs of wastewater. Among EDCs, natural and synthetic steroid hormones are recognized for their potential to mimic or interfere with normal hormonal functions (development, growth and reproduction), even at ultratrace levels (ng L−1). Although conjugated hormones are less active than free hormones, they can be cleaved and release the unconjugated estrogens through microbial processes before or during the treatment of wastewater. Due to the need to identify and quantify these compounds, a new fully automated method was developed for the simultaneous determination of the two forms of several steroid hormones (free and conjugated) in different water matrixes and in urine. SN - 1752-153X UR - https://doi.org/10.1186/s13065-016-0174-z DO - 10.1186/s13065-016-0174-z ID - Naldi2016 ER -