Table 10 Toxicity of tyrosine derivatives and standard drug based on OSIRIS property explorer
Molecule | Mutagenicity | Tumorigenic | Irritant | Reproductive effect | Drug likeness | Drug score |
|---|---|---|---|---|---|---|
Molecule_6 | Green | Green | Green | Green | 1.88 | 0.63 |
Molecule_8 | Green | Green | Green | Green | 2.25 | 0.62 |
Molecule_9 | Green | Green | Green | Green | 1.83 | 0.60 |
Molecule_10 | Green | Green | Green | Green | 2.46 | 0.66 |
Molecule_11 | Green | Green | Green | Green | 0.87 | 0.53 |
Molecule_12 | Green | Green | Green | Green | 2.46 | 0.67 |
Molecule_13 | Green | Green | Green | Green | 2.61 | 0.65 |
Molecule_14 | Green | Green | Green | Green | −2.08 | 0.39 |
Molecule_15 | Green | Green | Green | Green | 2.03 | 0.54 |
Molecule_17 | Green | Green | Green | Green | 4.74 | 0.54 |
Molecule_20 | Green | Green | Green | Green | 4.69 | 0.50 |
Molecule_21 | Green | Green | Green | Green | 5.29 | 0.55 |
Molecule_23 | Green | Green | Green | Green | 5.54 | 0.57 |
Molecule_24 | Green | Green | Green | Green | 5.43 | 0.53 |
Molecule_25 | Green | Green | Green | Green | 0.74 | 0.48 |
Molecule_26 | Green | Green | Green | Green | 4.88 | 0.45 |
Molecule_50 | Green | Green | Green | Green | 2.34 | 0.45 |
Molecule_51 | Green | Green | Green | Green | 1.46 | 0.60 |
Molecule_54 | Green | Green | Green | Green | 1.77 | 0.59 |
Molecule_58 | Green | Green | Green | Green | 4.31 | 0.51 |
Molecule_67 | Green | Green | Green | Green | 2.39 | 0.46 |
Molecule_99 | Green | Green | Green | Green | −0.06 | 0.46 |
Molecule_102 | Green | Green | Green | Green | −10.82 | 0.39 |
Molecule_103 | Green | Yellow | Red | Green | −15.1 | 0.18 |
Molecule_113 | Green | Green | Red | Green | −7.79 | 0.32 |
Molecule_115 | Green | Green | Green | Green | −7.28 | 0.33 |
Molecule_117 | Green | Green | Green | Green | −11.92 | 0.33 |
Molecule_141 | Green | Green | Green | Green | −17.18 | 0.34 |
Molecule_146 | Green | Green | Green | Green | −11.29 | 0.35 |
Molecule_154 | Green | Green | Green | Green | −8.91 | 0.31 |
Molecule_7 | Green | Green | Green | Green | 3.47 | 0.70 |
Molecule_52 | Green | Green | Green | Green | −2.79 | 0.21 |
Molecule_57 | Green | Green | Green | Green | −0.83 | 0.49 |
Molecule_59 | Green | Green | Green | Green | 4.36 | 0.52 |
Molecule_60 | Green | Green | Green | Green | 2.39 | 0.29 |
Celecoxib | Green | Green | Green | Green | −8.11 | 0.37 |