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Table 6 Antibacterial/antifungal inhibition area (mm) of 6aj derivatives

From: Synthesis and biological evaluation of new 1,3-thiazolidine-4-one derivatives of nitro-l-arginine methyl ester

Sample

Diameter of inhibition areaa (mm)

Bacterial strains

Yeasts strains

SA

SL

EC

PA

CA

CG

CP

6a

15.2 ± 0.12

19.3 ± 0.15

10.1 ± 0.06

13.1 ± 0.24

11.8 ± 0.35

15.2 ± 0.28

23.0 ± 0.19

6b

14.1 ± 0.08

20.1 ± 0.13

15.1 ± 0.23

11.2 ± 0.41

12.9 ± 0.06

15.2 ± 0.98

24.1 ± 0.65

6c

15.2 ± 0.16

18.1 ± 0.78

11.2 ± 0.63

11.9 ± 0.09

9.9 ± 0.62

13.8 ± 0.07

21.2 ± 0.33

6d

15.3 ± 0.68

18.2 ± 0.55

10.2 ± 0.37

13.2 ± 0.21

16.4 ± 0.78

24.2 ± 0.35

6e

12.1 ± 0.09

20.1 ± 0.43

10.1 ± 0.32

11.1 ± 0.19

12.1 ± 0.58

15.9 ± 0.55

25.3 ± 0.28

6f

15.2 ± 0.52

20.1 ± 0.26

12.2 ± 1.05

10.2 ± 0.36

12.1 ± 0.18

15.5 ± 0.48

25.1 ± 0.37

6g

13.1 ± 0.15

20.1 ± 0.72

10.1 ± 0.09

12.1 ± 0.28

15.9 ± 1.07

25.2 ± 0.39

6h

14.1 ± 0.09

20.3 ± 0.43

11.1 ± 0.30

10.2 ± 0.15

12.1 ± 0.86

13.8 ± 0.57

23.1 ± 0.22

6i

12.3 ± 0.08

21.1 ± 0.13

10.1 ± 0.23

12.2 ± 0.41

15.4 ± 0.06

16.4 ± 0.98

20.1 ± 0.65

6j

16.3 ± 0.34

21.2 ± 0.87

10.2 ± 0.51

13.1 ± 0.82

15.2 ± 0.74

15.2 ± 0.32

23.1 ± 0.47

5

14.9 ± 0.16

19.9 ± 0.12

11.9 ± 0.06

11.8 ± 0.19

13.8 ± 0.15

15.9 ± 0.17

19.9 ± 0.09

A

20.1 ± 0.57

21.2 ± 1.16

15.2 ± 0.67

C

16.3 ± 0.28

30.4 ± 0.35

20.1 ± 0.16

N

19.4 ± 0.51

19.5 ± 0.72

12.4 ± 0.42

  1. SA = Staphylococcus aureus ATCC 25923; SL = Sarcina lutea ATCC 9341; EC = Escherichia coli ATCC 25922; PA = Pseudomonas aeruginosa ATCC 27853; CA = Candida albicans ATCC 10231; CG = Candida glabrata ATCC MYA 2950; CP = Candida parapsilosis ATCC 22019; 5 = NO2-Arg-OMe; A = ampicillin; C = chloramphenicol; N = nystatin. 5 = L-NO2-Arg-OMe
  2. aMean values (n = 3) ± standard deviation