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Table 1 Response to saliva buffer containing added protein

From: Disposable screen printed sensor for the electrochemical detection of methamphetamine in undiluted saliva

 

Average peak height/nA (±1 SD)

% Decrease in peak height

1st peak (at +0.40 V)

2nd peak (at +0.25 V)

3rd peak (at −0.06 V)

1st peak

2nd peak

3rd peak

SSB

2865 ± 1369

3257 ± 1939

436 ± 30

   

SSB + 0.021 mg/mL mucin

2665 ± 728

2581 ± 893

481 ± 59

−7.0

−20.8

10.4

SSB + 0.021 mg/mL mucin + 0.3 mg/mL lysozyme

1952 ± 1009

1781 ± 1018

382 ± 70

−26.7

−31.0

−20.5

SSB + 0.021 mg/mL mucin + 3.0 mg/mL lysozyme

985 ± 275

717 ± 233

54 ± 29

−49.5

−59.7

−85.8

  1. (A) No addition and with the addition of (B) 0.021 mg/mL mucin; (C) 0.3 mg/mL lysozyme and 0.021 mg/mL mucin; and (D) 3 mg/mL lysozyme and 0.021 mg/mL mucin. The overlayer was treated with 0.2 mg/mL of OX1006 in 0.4 M sodium carbonate buffer (pH 10.8), containing 0.23 M NaCl and 0.1 % TX-100. Each sample was tested with 6 sensors. The SWV procedure is described in Fig. 6
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BMC Chemistry

ISSN: 2661-801X

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