From: Using water–solvent systems to estimate in vivo blood–tissue partition coefficients
Process | p | R2 | c0 | c1 |
---|---|---|---|---|
Blood–brain | 0.001 | 0.94 | 0.505 | 0.169 |
Blood–muscle | 0.2 | 0.32 | 0.077 | 0.021 |
Blood–liver | 0.2 | 0.33 | 0.281 | 0.045 |
Blood–lung | 0.06 | 0.64 | 0.239 | 0.122 |
Blood–kidney | 0.3 | 0.29 | 0.481 | 0.053 |
Blood–heart | 0.07 | 0.61 | 0.113 | 0.079 |
Blood–skin | 0.05 | 0.65 | −0.132 | 0.111 |
Blood–fat | 0.0009 | 0.95 | 0.007 | 0.285 |
Water–skin | 0.03 | 0.71 | 0.452 | 0.289 |
Skin-permeation | 0.02 | 0.80 | −5.519 | 0.403 |