Table 13 Top five results for two-variable blood–kidney partition coefficient
From: Using water–solvent systems to estimate in vivo blood–tissue partition coefficients
Solvent 1 | Solvent 2 | c0 | c1 | c2 | p | R2 |
|---|---|---|---|---|---|---|
Ethanol/water(20:80)vol | DMSO | 0.924 | 2.035 | −0.428 | 0.0001 | 0.998 |
Ethanol/water(30:70)vol | DMSO | 0.754 | 1.268 | −0.417 | 0.001 | 0.99 |
Ethanol/water (40:60)vol | DMSO | 0.617 | 0.916 | −0.410 | 0.001 | 0.99 |
2-Butanol | Tributyl phosphate | 0.408 | 0.799 | −0.698 | 0.002 | 0.99 |
Ethanol/water(20:80)vol | Formamide | 1.014 | 2.596 | −0.786 | 0.03 | 0.90 |