Table 12 Top five solvents for skin-permeation
From: Using water–solvent systems to estimate in vivo blood–tissue partition coefficients
Solvent | c0 | c1 | p | R2 |
|---|---|---|---|---|
Methyl tert-butyl ether | −5.588 | 0.492 | 0.00002 | 0.99 |
THF | −5.532 | 0.501 | 0.0002 | 0.99 |
Diethyl ether | −5.596 | 0.503 | 0.0004 | 0.99 |
Ethanol/water(40:60)vol | −5.147 | 1.237 | 0.001 | 0.94 |
Ethanol/water(30:70)vol | −4.967 | 1.683 | 0.002 | 0.94 |