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Table 11 Top five solvents for water–skin

From: Using water–solvent systems to estimate in vivo blood–tissue partition coefficients

Solvent

c0

c1

p

R2

THF

0.438

0.383

0.000003

0.997

Dibutylformamide

0.389

0.403

0.00002

0.99

1,4-Dioxane

0.474

0.401

0.00002

0.99

Acetone

0.395

0.410

0.00003

0.99

N-Formylmorphine

0.538

0.475

0.00003

0.99