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Table 1 Antiparasitic activity (IC50, μM) of the isolated compounds from Pelliciera rhizophorae

From: Phytochemical composition, antiparasitic and α–glucosidase inhibition activities from Pelliciera rhizophorae

Compounds

L. donovani

P. falciparum

T. cruzi

Vero cells

1

I

I

19.0 ± 0.6

I

2

I

I

I

I

3

2.4 ± 0.1

21.9 ± 0.6

I

64.8 ± 0.3

4

5.3 ± 0.2

I

I

140.8 ± 0.5

5

I

18.0 ± 0.4

I

131.1 ± 0.3

6

I

I

I

I

7

I

I

I

I

8

22.9 ± 0.2

I

I

154.9 ± 0.6

9

12.6 ± 0.2

9.7 ± 0.3

13.0 ± 0.4

I

10

3.4 ± 0.1

I

I

I

Anfotericine B

1.0 ± 0.12

ND

ND

ND

Chloroquine

ND

0.09 ± 0.01

ND

ND

Nifurtimox

ND

ND

1.6 ± 0.11

ND

  1. I inactive at 10 µg/mL, ND not determined