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Table 4 DPPH free radicals scavenging assay of compounds 1-4

From: Synthesis, anticholinesterase and antioxidant potentials of ketoesters derivatives of succinimides: a possible role in the management of Alzheimer’s

Compounds

Conc. (μg/mL)

Percent inhibition (mean ± SEM)

IC50 (μg/mL)

1

1000

72.41 ± 0.45***

440

 

500

52.49 ± 0.78***

 
 

250

35.60 ± 0.75***

2

1000

70.32 ± 0.61***

460

 

500

52.48 ± 0.56***

 
 

250

33.61 ± 0.66***

 

3

1000

60.40 ± 0.49***

535

 

500

54.64 ± 0.70***

 
 

250

30.59 ± 0.67***

 

4

1000

45.80 ± 0.61***

>1000

 

500

24.75 ± 0.64***

 
 

250

20.34 ± 0.58***

 

Ascorbic

1000

93.56 ± 0.37

20

acid

500

81.71 ± 0.54

 
 

250

78.61 ± 0.23

 
  1. Data is represented as mean ± SEM, n = 3
  2. Two-way ANOVA followed by Bonferroni test was applied for significant difference between standard drugs and test samples at 95 % confidence interval. Values significantly different as compare to positive control, ***P <0.001