Fig. 1
From: Crystal structures of increasingly large molecules: meeting the challenges with CRYSTALS software
The size of molecules charaterised by single crystal diffraction over the last hundred years. (top) The percentage of structures is shown as a function of size in each time period given. It is clear that the percentage of smaller structures decreases over time (going from blue to red) as the number of larger structures determined increases. (bottom) The size of the largest molecule for each period is shown, showing how the largest molecules reported have also increased over the years