Table 1 Preparation of resveralogues
From: A facile, stereoselective, one-pot synthesis of resveratrol derivatives
R’† | R† | Yield (%) | |
|---|---|---|---|
1 | 2-CN | 3,5-dimethoxy | 71 |
2 | 3-Cl | 4-N(Me)2 | 79 |
3 | 2-NO2 | 3,5-dimethoxy | 80 |
4 | 2-F | 3,5-dimethoxy | 74 |
5 | 2-NO2 | 4-OMe | 79 |
6 | 3-Cl | 3,5-dimethoxy | 68 |
7 | 3-CF3 | 4-N(Me)2 | 74 |
8 | 3,5-dimethyl | 3,5-dimethoxy | 81 |
9 | 2,4-difluoro | 3,5-dimethoxy | 74 |
10 | 4-Me | 3,5-dimethoxy | 84 |
11 | 4-CN | 3,5-dimethoxy | 80 |
12 | 4-OMe | 3,5-dimethoxy | 60 |
13 | 4-COOMe | 3,5-dimethoxy | 59 |
14 | 4-NO2 | 3,5-dimethoxy | 90 |
15 | 2,6-difluoro | 3,5-dimethoxy | 78 |
16 | 2,6-dichloro | 3,5-dimethoxy | 79 |