Skip to main content

Table 3 Percentage efficiency of Clot lysis of synthetic compounds 2 and 3a-i

From: Regioselective synthesis of 2-(bromomethyl)-5-aryl-thiophene derivatives viapalladium (0) catalyzed suzuki cross-coupling reactions: as antithrombotic and haemolytically active molecules

Compounds

Clot lysis %

2

2.73 ± 0.03

3a

9.76 ± 0.08

3c

12.3 ± 0.15

3b

5.29 ± 0.04

3d

3.71 ± 0.04

3e

1.96 ± 0.02

3f

8.05 ± 0.07

3 g

7.28 ± 0.06

3 h

4.37 ± 0.02

3i

31.5 ± 0.45

Water

0.43 ± 0.005

Streptokinase

87.2 ± 0.95

  1. The results are average ± S.D of triplicate experiments p < 0.05.