Figure 3
Treatment of Jurkat cells with triazole-containing alkyl β-D-glucopyranosides 4d and 4e and alkyl β-D-glucopyranosides C14G1 resulted in caspase-3 activation. Jurkat cells were treated with compounds at their respective IC50 concentration. The percentage of cells with activated caspase-3 as determined by emission of green fluorescence signal is indicated on y axis. Each bar represents average of three independent measurement values, and error bars their corresponding SD values. Data were analyzed using the two-tailed Student's paired t-test of compound treated cells vs. DMSO treated cells with P-values within statistically significant range of P < 0.0001 (*) and P < 0.008 (†).