Assessing antibiotic sorption in soil: a literature review and new case studies on sulfonamides and macrolides

BMC Chemistry

Table 2 Sorption coefficients of tylosin

Soil Type	K_d(L/kg)	Concentration range used	Measurement technique	Reference
Sandy Loam	58.1 – 148.0	500 ppb	LC-MS	[37]
			LC-fluorescence
	92	1000 ppm	ELISA	[35]
	101.02-13961.00	10, 100, 200, 1000 ppb	HPLC-MS	ED
			(ion trap)	Method 2
	6737-33871	1, 5, 10, 100, 200, 500, 1000 ppb	HPLC-MS/MS	ED
				Method 3
	42	5 ppm	HPLC-UV	[36]
			(λ = 290 nm)
Clay Loam	66	1000 ppm	ELISA	[35]
	156 ± 8	3 ppm	HPLC-MS (SIM)	[6]
	1.76 – 6.19	0.5, 5, 50 ppm	HPLC-UV	[25]
			(λ = 290 nm)
	65	5 ppm	HPLC-UV	[36]
			(λ = 290 nm)
Loam	59.35-1176.00	10, 100, 200, 1000 ppb	HPLC-MS (ion trap)	ED
				Method 2
	1684-172480	1, 5, 10, 100, 200, 500, 1000 ppb	HPLC-MS/MS	ED
				Method 3
	5.77 - 12.4	0.5, 5, 50 ppm	HPLC-UV	[25]
			(λ = 290 nm)
Loamy Sand	8.3 ± 1.2	500 ppb	LC-MS	[37]
			LC-fluorescence
	8.9 ± 0.4	3 ppm	HPLC-MS (SIM)	[6]
Sand Soil	10.8 ± 0.7	500 ppb	LC-MS	[37]
			LC-fluorescence
	24	5 ppm	HPLC-UV	[36]
			(λ = 290 nm)
Clay%: 0.2 - 51.6%	10.4-387.0	3 - 7.5 ppm	HPLC-MS (SIM)	[38]
	(Average = 129.5)
Clay%: < 3 - 69% (K_d increases with clay %)	2.23-5520	5 - 43 μmol/L	HPLC-UV,	[2]
	(Tylosin A)		(λ = 280 nm)
	547-4745	5 - 43 μmol/L	HPLC-UV,	[2]
	(Tylosin D)		(λ = 280 nm)
	597-6520	5 - 43 μmol/L	HPLC-UV,	[2]
	(Tylosin A-Aldol)		(λ = 280 nm)

Note: Results are soil dependent. ED: experimentally determined. Methodology can be found in the additional files. K_ow ranges for tylosin A and it’s metabolites: tylosin A: 0.552-32.6587; tylosin B: 1.535-78.343; tylosin C: 0.676-41.495;tylosin D: 0.309-17.947. K_ow values calculated using Advanced Chemistry Development (ACD/Labs) Software V11.02 (© 1994-2012 ACD/Labs).

ISSN: 2661-801X