Table 1 Effects of compounds 1–19 on heart rate and blood pressure
From: Biological effects of a new set 1,2,4-triazolo[1,5-a]quinazolines on heart rate and blood pressure
Compound | % change in heart rate | Decrease in the rats arterial pressure (mm H) | |
|---|---|---|---|
Decrease | Increase | ||
1 | - | 33.3 | 0 |
2 | 0 | - | 0 |
3 | - | 14.3 | 6.5 |
4 | 22.7 | - | 2.6 |
5 | 15 | - | 0 |
6 | 0 | 40 | 0 |
7 | 5.9 | - | 0 |
8 | 14.3 | - | 0 |
9 | 20 | - | 9.1 |
10 | 5.9 | - | 0 |
11 | 0 | - | 2.6 |
12 | 16.7 | - | 2.6 ↑ |
13 | - | 8.3 | 0 |
14 | - | 7.7 | 7.8 |
15 | 10 | - | 5.2 |
16 | 0 | - | 0 |
17 | 5.9 | - | 6.5 |
18 | 5.9 | - | 0 |
19 | - | 28.5 | 6.5 |