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Table 1 Intra-day and inter-days precision and accuracy for determination of montelukast in spiked human plasma

From: Development and validation of LC/MS/MS method for the simultaneous determination of montelukast, gliclazide, and nifedipine and its application to a pharmacokinetic study

 

Theoretical concentration (ng/mL)

Parameters

Intra-day reproducibility

Inter-days reproducibility

10

20

40

80

120

400

800

10

20

40

80

120

400

800

Concentration found (ng/mL)

Mean

10.93

19.9

38.5

77.43

109.16

372.45

808.55

10.37

18.92

37.95

78.23

105.58

392.03

816.69

Precision

1.69

7.79

4.49

8.73

4.56

14.13

7.68

13.74

12.52

14.01

13.81

11.34

14.14

12.84

Accuracy (%)

109.32

99.5

96.24

96.79

109.16

93.11

101.07

103.66

94.59

94.89

97.79

105.58

98.01

102.09