Sustained release formulation of an anti-tuberculosis drug based on para-amino salicylic acid-zinc layered hydroxide nanocomposite

Table 3 Correlation coefficient (R ² ), and rate constants (k) obtained by fitting the data of 4-amino salicylic acid release from 4-ASA nanocomposite into PBS solution at pH 4.8 and 7.4

pH	Saturation release (%)	R²			pseudo-second order
		pseudo-first order	pseudo-second order	Parabolic diffusion model	rate constant (k) (mg/min)
7.4	92	0.9339	0.9982	0.8961	3.9 × 10^-5
4.8	100	0.8839	0.9999	0.5925	1.0 × 10^-4

ISSN: 2661-801X