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Table 3 Correlation coefficient (R 2 ), and rate constants (k) obtained by fitting the data of 4-amino salicylic acid release from 4-ASA nanocomposite into PBS solution at pH 4.8 and 7.4

From: Sustained release formulation of an anti-tuberculosis drug based on para-amino salicylic acid-zinc layered hydroxide nanocomposite

pH Saturation release (%)   R2 pseudo-second order
   pseudo-first order pseudo-second order Parabolic diffusion model rate constant (k) (mg/min)
7.4 92 0.9339 0.9982 0.8961 3.9 × 10-5
4.8 100 0.8839 0.9999 0.5925 1.0 × 10-4