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Table 3 Kinetic analysis for the three active substances, the NPK method

From: Comparative kinetic analysis on thermal degradation of some cephalosporins using TG and DSC data

  Process λ (%) E (kJ mol-1) A (min-1) n m Sestak-Bergrren Eq ∑λ·E (kJ mol-1)
Cefadroxil 1 95.4 258.6±7.1 1.33·1027 1 - (1-α) 264.5±9.8
(DSC data) [20] 2 4.6 385.4±83.8 1.07·1037 - 1/3 α1/3
Cephalexin 1 77.2 220.2±9.7 8.04·1023 1 - (1-α) 248.0±18.2
(DSC data) [11] 2 18.9 412.4±162.2 3.40·1045 5/3 1 α5/3 · (1-α)
Cefoperazone 1 86.7 170.2±17.4 2.70·1018 2 1 α · (1-α)2 179.9±14.9
(DSC data) 2 13.3 243.8±17.6 7.18·1026 2 1 α · (1-α)2
Cefadroxil 1 93.9 226.7±8.3 4.95·1023 2 1 α · (1-α)2 231.9±14.1
(TG data) 2 4.5 428.1±40.3 7.88·1044 - 0.1 α0.1  
Cephalexin 1 84.0 181.2±13.2 7.37·1019 1 - (1-α) 220.6±13.2
(TG data) 2 16.0 411.9±75.4 5.10·1045 0.1 - (1-α)0.1
Cefoperazone 1 71.4 141.5±6.0 9.16·1014 3 - (1-α)3 156.4±12.4
(TG data) 2 22.5 245.6±83.6 5.80·1026 - 3 α3