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Table 1 Intra- and inter-day precision and accuracy of LND in rabbit and human plasma

From: Development and validation of ultra-performance liquid chromatographic method with tandem mass spectrometry for determination of lenalidomide in rabbit and human plasma

Nominal conc. (ng/mL) Run Rabbit plasma Human plasma
   Measured conc. (ng/mL ± SD) Precision (CV,%) Accuracy (recovery,%) Measured conc. (ng/mL ± SD) Precision (CV,%) Accuracy (recovery,%)
  Intraday variation (six replicate at each concentration)
0.26 1 0.27 ± 0.02 6.98 103 0.29 ± 0.01 3.60 110
  2 0.26 ± 0.03 9.51 101 0.29 ± 0.03 9.61 109
  3 0.28 ± 0.03 12.2 108 0.30 ± 0.03 9.53 113
1.28 1 1.30 ± 0.07 6.74 101 1.32 ± 0.08 5.80 103
  2 1.32 ± 0.04 3.09 103 1.34 ± 0.05 3.51 105
  3 1.36 ± 0.06 4.78 106 1.37 ± 0.06 4.16 107
64.0 1 59.3 ± 5.35 9.02 92.7 59.8 ± 5.95 9.94 93.5
  2 64.8 ± 4.26 6.57 101 64.8 ± 5.42 8.36 101
  3 58.5 ± 6.19 10.60 91.4 63.8 ± 5.91 9.26 99.7
800 1 832 ± 17.70 2.14 104 814 ± 43.60 5.36 102
  2 778 ± 19.30 2.48 97.2 790 ± 34.50 4.37 98.8
  3 775.8 ± 38.60 4.97 97.0 769 ± 15.10 1.97 96.1
  Intraday variation (18 replicates at each concentration)
0.26   0.27 ± 0.03 9.67 104 0.29 ± 0.03 9.72 111
1.28   1.32 ± 0.06 4.80 103 1.34 ± 0.06 4.54 105
64   60.9 ±5.80 9.49 95.1 62.9 ± 5.91 9.40 98.3
800   795 ±36.80 4.62 99.4 791 ± 36.60 4.62 99.2