Compound | RLU Reading | Inhibition% | IC50 ± S.D | ||||
---|---|---|---|---|---|---|---|
concentration (μg mL-1) | 100 | 50 | 12.5 | 100 | 50 | 12.5 | |
4 | 1859.3 | 1831.4 | 1540.9 | −75.16 | −72.53 | −45.16 | >100 |
5 | 74.7 | 127.7 | 378.3 | 92.96 | 87.97 | 64.36 | <12.5 |
6 | 172.8 | 435.2 | 873.8 | 83.72 | 59 | 17.68 | 39.3 ± 12.3 |
7 | −1.7 | −1.1 | 5 | 100.16 | 100.1 | 99.53 | <12.5 |
8 | 200.5 | 402.6 | 905.1 | 81.11 | 62.08 | 14.73 | 34.6 ± 9.8 |
9 | 777.9 | 939.1 | 945.2 | 26.72 | 11.53 | 10.96 | >100 |
10 | 306.9 | 736.1 | 1520 | 71.09 | 30.66 | −43.18 | 69.6 ± 1.9 |
11 | 823.7 | 958.1 | 1129 | 22.41 | 9.74 | −6.39 | >100 |
12 | 1028.5 | 970.8 | 1334 | 3.11 | 8.55 | −25.72 | >100 |
13 | 503.6 | 705.5 | 1060 | 52.56 | 33.54 | 0.13 | 90.7 ± 13.2 |
14 | 74.3 | 219.6 | 663.1 | 93.01 | 79.31 | 37.53 | 21.5 ± 6.7 |
15 | 109.6 | 222.1 | 444.6 | 89.68 | 79.08 | 58.12 | <12.5 |
16 | 15.7 | 23.1 | 71.7 | 98.52 | 97.82 | 93.25 | <12.5 |
17 | 20.5 | 48.3 | 226.7 | 98.07 | 95.45 | 78.64 | <12.5 |
18 | 637.3 | 879.9 | 1199.9 | 39.96 | 17.11 | −13.03 | >100 |
19 | 379.6 | 676.6 | 1047.4 | 64.24 | 36.26 | 1.33 | 73.6 ± 0.4 |
20 | 99.5 | 143.6 | 389.8 | 90.62 | 86.47 | 63.28 | <12.5 |
Gatifloxacin | 162.4 | 360.6 | 852.1 | 84.7 | 66.03 | 19.73 | 31 ± 0 |