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Table 3 In vitro cytotoxicity of compounds 1–5

From: Microbial transformation of anti-cancer steroid exemestane and cytotoxicity of its metabolites against cancer cell lines

Compound Codes

HeLa (Cervical cancer) (IC50± S.D.) μM

PC-3 (Prostate cancer) (IC50±S.D.) μM

1

>50

>50

2

16.83±0.96

24.87±0.72

3

>50

>50

4

37.20 ± 0.88

>50

5

>50

>50

Doxorubicin

3.10 ± 0.20

0.91 ± 0.12