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Table 1 Comparison of multi-analyte and established analysis methods

From: Multi-analyte approach for determining the extraction of tobacco constituents from pouched snus by consumers during use

Analyte Mean ± SD value from established method, per gram basis (N=5) Mean ± SD value from multi-analyte method, per whole 1 g pouch basis (N=5) Percentage change relative to established method p value
Water (%) 48.7±1.38 49.4±0.90 1.4 0.391
NAB (ng) 22.7±0.66 21.6±1.05 −4.8 0.092
NAT (ng) 377.7±5.26 382.2±5.91 1.2 0.246
NNK (ng) 166.1±4.25 165.2±6.19 −0.5 0.783
NNN (ng) 498.9±18.03 495.6±23.10 −0.7 0.811
Nicotine (mg) 8.2±1.00 9.9±0.13 20.2 0.021
Propylene glycol (mg) 35.7±0.58 35.3±0.43 −1.1 0.258
Sodium (mg) 21.5±0.29 21.3±0.75 −0.9 0.610
Chloride (mg) 29.8±1.18 29.1±1.57 −2.3 0.486
Ammonium (μg) 1358±32.0 1406±39.3 3.5 0.071
Nitrate (μg) 1500±16.6 1462±12.8 −2.6 0.004
pH 8.5±0.02 8.5±0.01 0.5 0.002