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Table 1 Comparison of multi-analyte and established analysis methods

From: Multi-analyte approach for determining the extraction of tobacco constituents from pouched snus by consumers during use

Analyte

Mean ± SD value from established method, per gram basis (N=5)

Mean ± SD value from multi-analyte method, per whole 1 g pouch basis (N=5)

Percentage change relative to established method

p value

Water (%)

48.7±1.38

49.4±0.90

1.4

0.391

NAB (ng)

22.7±0.66

21.6±1.05

−4.8

0.092

NAT (ng)

377.7±5.26

382.2±5.91

1.2

0.246

NNK (ng)

166.1±4.25

165.2±6.19

−0.5

0.783

NNN (ng)

498.9±18.03

495.6±23.10

−0.7

0.811

Nicotine (mg)

8.2±1.00

9.9±0.13

20.2

0.021

Propylene glycol (mg)

35.7±0.58

35.3±0.43

−1.1

0.258

Sodium (mg)

21.5±0.29

21.3±0.75

−0.9

0.610

Chloride (mg)

29.8±1.18

29.1±1.57

−2.3

0.486

Ammonium (μg)

1358±32.0

1406±39.3

3.5

0.071

Nitrate (μg)

1500±16.6

1462±12.8

−2.6

0.004

pH

8.5±0.02

8.5±0.01

0.5

0.002