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Table 2 In vitro antiproliferative activity of C. libanotis, C. monspeliensis and C. villosus hexane extracts against J774.A1 macrophages, A-375 human melanoma cells and MCF-7 breast cancer cells at 72 h

From: Antiproliferative activity of hexane extract from Tunisian Cistus libanotis, Cistus monspeliensis and Cistus villosus

IC5072 h
Compound J774A.1 MCF7 A375
Cistus libanotis N.D. N.D. N.D.
Cistus monspeliensis N.D. N.D. 52.44 ± 3.69
Cistus villosus N.D. N.D. N.D.
6-mercaptopurine 0,003 48,23 142,36
N.D. = not detected    
  1. IC50 values for different cancer cell lines are expressed in mg /mL for extracts and in μM for 6-MP, used as reference drug. The IC50 value is the concentration of compound that affords 50% reduction in cell growth after 3 days incubation. Values are expressed as mean ± SD, n = 3.