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Table 2 In vitro antiproliferative activity of C. libanotis, C. monspeliensis and C. villosus hexane extracts against J774.A1 macrophages, A-375 human melanoma cells and MCF-7 breast cancer cells at 72 h

From: Antiproliferative activity of hexane extract from Tunisian Cistus libanotis, Cistus monspeliensis and Cistus villosus

IC5072 h

Compound

J774A.1

MCF7

A375

Cistus libanotis

N.D.

N.D.

N.D.

Cistus monspeliensis

N.D.

N.D.

52.44 ± 3.69

Cistus villosus

N.D.

N.D.

N.D.

6-mercaptopurine

0,003

48,23

142,36

N.D. = not detected

   
  1. IC50 values for different cancer cell lines are expressed in mg /mL for extracts and in μM for 6-MP, used as reference drug. The IC50 value is the concentration of compound that affords 50% reduction in cell growth after 3 days incubation. Values are expressed as mean ± SD, n = 3.