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Table 1 Growth inhibition effect of various constituents of Cyrtomium fortumei (J.) Smith on different cell lines

From: Discovery and antitumor activities of constituents from Cyrtomium fortumei(J.) Smith rhizomes

Test extracts and compounds Inhibitory Rate for Different Cell Lines (%, mean ± SD)a
  MGC-803b PC3c A375d NIH3T3e
Petroleum ether extract f 56.7 ± 3.7 68.0 ± 1.9 60.5 ± 3.2 7.1 ± 3.8
Ethyl acetate extract f 80.3 ± 2.8 89.6 ± 1.5 88.7 ± 3.3 45.6 ± 4.0
n-BuOH extract f 87.2 ± 3.9 80.2 ± 2.4 85.2 ± 3.7 53.5 ± 8.6
ADM 93.2 ± 1.6 95.1 ± 2.6 95.2 ± 2.4 98.5 ± 1.7
Protocate chaldehyde (1) 17.8 ± 3.1 30.5 ± 2.4 25.7 ± 3.1 12.1 ± 3.7
Woodwardinsaure methylester (2) 47.9 ± 9.3 33.2 ± 2.8 41.4 ± 5.6 15.2 ± 2.6
PPI (3) 67.1 ± 5.3 57.2 ± 4.2 45.8 ± 7.8 24.8 ± 3.4
Physcion (5) 28.9 ± 2.2 20.7 ± 1.2 15.7 ± 5.9 4.5 ± 2.6
Ursolic acid (6) 52.6 ± 2.4 55.8 ± 3.1 43.2 ± 1.3 23.4 ± 3.3
Sitost-4-en-3-one (7) 35.8 ± 2.6 15.3 ± 5.8 26.4 ± 5.1 5.2 ± 2.7
Betulin (8) 45.1 ± 3.1 18.4 ± 3.1 33.9 ± 5.6 29.8 ± 2.5
3′,4′,5-Trihydroxy-3,7-dimethoxyflavone (9) 25.6 ± 3.9 20.3 ± 2.5 11.2 ± 6.2 10.0 ± 2.9
Woodwardinic acid (10) 25.1 ± 5.3 25.2 ± 1.3 38.6 ± 4.0 6.9 ± 2.0
Sutchuenoside A (12) 19.9 ± 9.8 12.3 ± 4.4 34.8 ± 5.3 8.8 ± 4.2
Kaempferol-3, 7-O-α-L-dirhamnoside (14) 21.5 ± 7.0 17.8 ± 5.5 36.7 ± 3.9 23.1 ± 3.2
(-)-Epicatchin (15) 45.5 ± 4.1 50.6 ± 1.6 45.3 ± 3.2 22.5 ± 3.8
(+)-Catechin hydrate (16) 52.1 ± 5.7 49.6 ± 2.3 46.8 ± 1.1 28.9 ± 4.3
Kampferol (17) 54.5 ± 2.4 44.3 ± 2.5 47.3 ± 1.9 12.2 ± 3.4
Crassirhizomoside A (20) 11.4 ± 2.3 20.8 ± 6.0 34.9 ± 2.7 12.5 ± 5.2
Kaempferol-3-O-(3-O-acetyl-α-L-rhamnopyranoside) (21) 22.6 ± 8.0 15.6 ± 6.1 17.8 ± 3.3 9.9 ± 6.1
  1. Note: a Inhibitory percentage of cells treated with 20 μM of each compound for 72 h and SD = standard deviation; b Stomach cancer; c Prostate cancer; d Malignant melanoma; e Mouse fibroblasts; f Inhibitory percentage of cells treated with 200 μg/mL of each extract for 72 h.