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Table 1 H-5 chemical shift of some imidazo[1,2-a]pyridines substituted with angular EWG at position 3

From: Intramolecular H-bonding interaction in angular 3-π-EWG substituted imidazo[1,2-a]pyridines contributes to conformational preference

Name δ H-5aExp δ H-5a Reference
imidazo[1,2-a]pyridine 8.05 8.05 [8]
3-nitroso-2-phenyl imidazo[1,2-a]pyridine 9.89 9.97-10 [10]
3-formyl-2-phenyl imidazo[1,2-a]pyridine 9.68 9.66 [11]
3-formyl imidazo[1,2-a]pyridine   9.52 [12]
3-benzoyl imidazo[1,2-a]pyridine 9.75 9.75 [13]
3-acetyl-2-methyl imidazo[1,2-a]pyridine 9.58 9.81 [14]
3-(2-chloroacetyl) imidazo[1,2-a]pyridine 9.48 9.48 [13]
3-nitro imidazo[1,2-a]pyridine 9.38 9.40 [5]
3-nitro-2-(4-nitrophenyl) imidazo[1,2-a]pyridine 9.50b 9.95c [15]
  1. a HNMR taken in CDCl3 unless otherwise stated. b Solvent DMSO-d6. c Solvent TFAA.