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Table 3 Integral toxicity index of active pure principles before and after exposure to 90 h of simulated sunlight

From: Photostability and toxicity of finasteride, diclofenac and naproxen under simulating sunlight exposure: evaluation of the toxicity trend and of the packaging photoprotection

Active principle

Photodegradation time (h)

ΔI0

ΔI

It = ΔI/ΔI0

Finasteride

0

3.26 ± 0.02

1.65 ± 0.02

0.51

90

3.46 ± 0.04

1.35 ± 0.03

0.39

Diclofenac

0

3.45 ± 0.02

2.66 ± 0.01

0.77

90

4.77 ± 0.02

2.25 ± 0.02

0.47

Naproxen

0

3.06 ± 0.01

2.35 ± 0.02

0.77

 

90

4.06 ± 0.03

0.55 ± 0.01

0.14

  1. Values comes from at least 3 tests.