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Table 4 Analysis of CLM in the presence of common excipients by the proposed assay

From: Novel microwell assay with high throughput and minimum consumption for organic solvents in the charge transfer-based spectrophotometric determination of clarithromycin in pharmaceutical formulations

Excipient

Recovery (% ± SD)a

Starch (50)b

97.9 ± 1.54

Microcrystalline cellulose (10)

100.2 ± 0.25

Silica gel (10)

98.5 ± 1.34

Talc (10)

97.4 ± 0.89

Titanium oxide (10)

101.3 ± 1.02

Magnesium stearate (10)

97.2 ± 1.54

Average ± SD

98.8 ± 1.65

  1. aValues are mean of three determinations.
  2. bFigures in parenthesis are the amounts in mg added per 50 mg of CLM.