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Table 1 Optimum conditions for the charge-transfer reaction of CLM with DDQ

From: Novel microwell assay with high throughput and minimum consumption for organic solvents in the charge transfer-based spectrophotometric determination of clarithromycin in pharmaceutical formulations

Condition

Studied range

Optimum

DDQ conc. (mg mL−1)

0 − 4

1

Solvent

Differenta

Methanol

Reaction time (min)

0 − 30

5

Temperature (°C)

25 − 60

25

λmax (nm)

400 − 600

450

  1. aSolvents tested: methanol, ethanol, propanol, butanol, acetone, and acetonitrile.