Figure 7

Aligned poses of compounds 5j and 10. (a) Best aligned pose of the less active compound 5j (MIC 0.8134 μmol/mL) overlaid onto the pharmacophore model (model-1). (b) Best aligned pose of the less active compound 10 (MIC 1.4230 μmol/mL) overlaid onto the pharmacophore model (model-1).