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Table 7 Assay results for the determination of LEV and AMB in their prepared tablets

From: Micellar liquid chromatographic method for the simultaneous determination of Levofloxacin and Ambroxol in combined tablets: Application to biological fluids

Preparation Amount taken Amount found % Found Comparison method (35)
(μg/mL) (μg/mL)
LEV AMB LEV AMB LEV AMB LEV AMB
Prepared tablet (250 mg LEV+60 mg AMB) 5.0 6.0 25.1500 6.0020 100.60 100.04 100.10 100.68
20.0 1.2 4.9200 1.2010 98.40 100.12 99.02 103.35
25.0 4.8 19.7780 4.8250 98.89 102.00 98.16 101.60
X ¯      100.20* 100.72 99.09 101.88
± SD      ±1.64 ±1.11 ±0.97 ±1.36
% RSD      1.63 1.10 0.98 1.33
% Error      0.94 0.64 0.57 0.77
t      0.233 1.143   
F      1.418 1.495   
  1. N.B. Each result is the average of three separate determinations.
  2. The values of tabulated t and F tests are 2.78 and 19.00 respectively at p = 0.05 [38].
  3. Average LEV concentration found in tablet 250.50 mg and average AMB found 60.14 mg per tablet.