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Table 3 Assay results for the determination of LEV and AMB in pure form

From: Micellar liquid chromatographic method for the simultaneous determination of Levofloxacin and Ambroxol in combined tablets: Application to biological fluids

Compound

Proposed method

Comparison method (35)

Amount taken (μg/mL)

Amount found (μg/mL)

% Found

% Found

LEV

1.0

0.9897

98.97

99.35

 

2.0

2.0161

100.81

100.96

 

12.0

11.8548

98.79

99.49

 

24.0

24.0249

100.10

 
 

28.0

28.1452

100.52

 
 

36.0

36.0484

100.13

 
 

44.0

43.8196

99.59

 

X ¯  ± SD

  

99.84 ± 0.76

99.93 ± 0.89

t-test

  

0.16 (2.31)

 

F-test

  

1.37 (5.14)

 

AMB

1.0

1.0294

102.94

100.26

 

4.0

3.9703

99.27

99.53

 

12.0

11.9920

99.93

100.21

 

16.0

16.0027

100.02

 
 

20.0

20.0134

100.07

 

X ¯  ± SD

  

100.45 ± 1.43

100.00 ± 0.41

t-test

  

0.51 (2.45)

 

F-test

  

12.31 (19.25)

 
  1. N.B. Each result is the average of three separate determinations.
  2. The figures between parentheses are the tabulated t and F values at P = 0.05 [38].
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BMC Chemistry

ISSN: 2661-801X

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